Managing Fisheries and Conserving Fishes: A Difficult Balancing Act

The Nile Fishes and Fisheries

A PKGarious Balancing Act

The pathologically hypertrophied and failing heart is a battlefield in a war that would make even George Lucas proud. On the one side, you have hemodynamic, neurohormonal, morphological, and cellular/molecular dark forces urging the ventricle toward decompensation and ultimate demise. On the other, Jedi signaling cascades try valiantly to stave off the impending disaster. Alas, unlike the movie...

A balancing act for autophagin.

Autophagy is a tightly regulated catabolic process whereby cells degrade their constituents to dispose of unwanted cytoplasmic elements and recycle nutrients for cellular remodeling. Studies of autophagy in mammals have elicited substantial interest because it is linked to a range of physiologic and pathologic states. In this issue of the JCI, Mariño et al. uncover a role for autophagy in a bal...

Persistence and Java - A Balancing Act

Large scale and long-lived application systems, enterprise applications, require persistence, that is provision of storage for many of their data structures. The Javatm programming language is a typical example of a strongly-typed, object-oriented programming language that is becoming popular for building enterprise applications. It therefore needs persistence. The present options for obtaining...

Mitochondrial biogenesis and clearance: a balancing act.

Mitochondria are semi-autonomous organelles of prokaryotic origin that are postulated to have been acquired by eukaryotic cells through an early endosymbiotic event. Except for their main role in energy production, they are also implicated in fundamental cellular processes, including ion homeostasis, lipid metabolism, and initiation of apoptotic cell death. Perturbed mitochondrial function has ...